Program Highlights
- Targeting an integrin receptor on the muscle cell surface
- Integrin target is upregulated as a compensatory mechanism in multiple types of muscular dystrophy
- Acts as a substitute for dystrophin, helping to stabilize the muscle membrane, increasing muscle strength, and decreasing muscle damage
- Mutations in the target receptor alone actually causes a human congenital myopathy similar to muscular dystrophy
- Potential to combine across multiple muscular dystrophy indications because the target integrin is upregulated across multiple forms of muscular dystrophy
Development Status
- This program is currently in preclinical development